Research At a Glance
- Research Category
- Neuroendocrine & Vascular Research
- Peptide Length
- 28 amino acids (vasoactive intestinal peptide)
- Purity
- ≥ 98% (HPLC)
- Published Studies
- 15,000+ indexed
- Storage
- Lyophilized: −20 °C long term, 2–8 °C short term. Reconstituted: 2–8 °C, use within 30 days.
Published-study figures are approximate PubMed result counts and indicate the volume of available literature only. Purity reflects third-party analytical testing on the corresponding lot; see the Quality Assurance Center for lot-matched certificates.
What It Is
A 28-amino-acid peptide widely distributed in the central and peripheral nervous systems, acting through VPAC1 and VPAC2 G-protein-coupled receptors, structurally related to PACAP and secretin-family peptides.
Research Mechanism
VIP/VPAC signaling has been studied for its immunomodulatory effects, including shifting cytokine profiles in immune cell culture models, as well as its role in synchronizing neurons of the suprachiasmatic nucleus (SCN) — the brain’s central circadian pacemaker (Vosko et al., 2007, review in General and Comparative Endocrinology — search PubMed ). It is also studied in gastrointestinal and pulmonary smooth-muscle relaxation models.
Research Applications
- Circadian pacemaker (SCN) signaling research
- Immune modulation and cytokine profile studies
- GI and pulmonary smooth-muscle models
Research Use Only
Provided for in-vitro laboratory research only. Not a drug, supplement, or cosmetic. Not for human or animal use.
Certificate of Analysis
Every lot is independently tested and lot-matched. View Certificates of Analysis